PPARα/δ agonist 3, CAS 3050611-33-8

Product Description: PPARα/δ agonist 3 (Compound 8) is the orally active agonist for PPAR, that activates PPARα, PPARδ and PPARγ with EC50s of 5.6, 3.4 and 1278 nM, respectively. PPARα/δ agonist 3 exhibits anticholestatic activity in mouse ANIT- or CDCA (HY-76847)-induced cholestatic liver disease models[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C23H25F3N2O4

References: [1]Fu Z, et al., Design, synthesis, and biological evaluation of imidazolidinone derivatives as potent PPARα/δ agonists for the treatment of cholestatic liver diseases. Eur J Med Chem. 2025 Mar 15;286:117284.

CAS Number: 3050611-33-8

Molecular Weight: 450.45

Research Area: Metabolic Disease

Target: PPAR

• SKU: MEXHY-168485-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168485-0
• Package Unit: Get quote
• Quantity Unit: STK