PPARγ modulator-2, CAS 2897652-01-4

Product Description: PPARγ modulator-2 (Compound (R)-2n) is the reversible modulator for PPARγ that inhibits PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. PPARγ modulator-2 reduces blood glucose, improves the glucose tolerance and insulin tolerance, and exhibits anti-diabetic efficacy in db/db mouse models[1].

Formula: C26H21NO7S3Se

References: [1]Chen F, et al., Identification of Novel Organo-Se BTSA-Based Derivatives as Potent, Reversible, and Selective PPARγ Covalent Modulators for Antidiabetic Drug Discovery. J Med Chem. 2025 Jan 9;68(1):819-831.

CAS Number: 2897652-01-4

Molecular Weight: 634.60

Research Area: Metabolic Disease

Target: PPAR

• SKU: MEXHY-170874-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170874-0
• Package Unit: Get quote
• Quantity Unit: STK