PPO-allene

Product Description: PPO-allene is a covalent botulinum neurotoxin (BoNT) light chain inhibitor (IC50: 20.9 μM). PPO-allene (0.3 mg/kg, i.v.) demonstrates an in vivo half-life of approximately 1.5 h in mice[1].

Formula: C29H28N4O3

References: [1]Lin M, et al. Bifunctional Inhibition of Botulinum Neurotoxin A Protease: Unexpected Active Site Inhibition Enhances Covalent Targeting of an Allosteric Site. J Med Chem. 2025 Apr 24;68(8):8796-8816.

Molecular Weight: 480.56

Research Area: Neurological Disease

Target: Bacterial

• SKU: MEXHY-176052-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-176052-0
• Package Unit: Get quote
• Quantity Unit: STK