PRC1-IN-1, CAS 2396639-29-3

Product Description: PRC1-IN-1 (compound RB-4) is an inhibitor of the polycomb repressive complex PRC1 (IC50=2.3 μM), targeting RING1B-BMI1, RING1A-BMI1, and RING1B-PCGF1 with IC50s of 2.8, 2.6, and 1.8 μM, respectively[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C24H19ClFN3O2

References: [1]Yao Y, et al. Development of PRC1 Inhibitors Employing Fragment-Based Approach and NMR-Guided Optimization. J Med Chem. 2025 Jan 23;68(2):1382-1396.

CAS Number: 2396639-29-3

Molecular Weight: 435.88

Research Area: Others

Target: E1/E2/E3 Enzyme

• SKU: MEXHY-170823-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170823-0
• Package Unit: Get quote
• Quantity Unit: STK