PRDX1-IN-3, CAS 2566976-46-1

Product Description: PRDX1-IN-3 (compound 19-048) is a PRDX1 covalent inhibitor with anti-colorectal cancer activity. PRDX1-IN-3 can effectively inhibit the proliferation of colorectal cancer cells, and its antitumor effect on nude mice with colorectal cancer carrying PRDX1 gene knockout is significantly reduced. PRDX1-IN-3 also upregulates the downstream genes of the p53 signaling pathway to exert an anticancer effect[1].

Applications: Cancer-programmed cell death

Formula: C33H46N2O5

References: [1]Xu H, et al. Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1. Signal Transduct Target Ther. 2023 Feb 3;8(1):51.

CAS Number: 2566976-46-1

Molecular Weight: 550.73

Research Area: cancer

Target: MDM-2/p53;Reactive Oxygen Species

• SKU: MEXHY-171272-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171272-0
• Package Unit: Get quote
• Quantity Unit: STK