PRMT5-IN-48, CAS 2640287-77-8

Product Description: PRMT5-IN-48 (compound D3) is an orally effective PRMT5 inhibitor (IC50=20.7 nM) with anticancer activity. PRMT5-IN-48 can inhibit the growth of various cancer cells, induce apoptosis (apoptosis), and arrest the cell cycle at the G0/G1 phase. PRMT5-IN-48 can be used for non-Hodgkin lymphoma (NHL) research[1].

Applications: Cancer-programmed cell death

Formula: C30H37N5O3

References: [1]Li QQ, et al. Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(2H)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma. J Med Chem. 2025 Jan 9;68(1):108-134.

CAS Number: 2640287-77-8

Molecular Weight: 515.65

Research Area: cancer

Target: Histone Methyltransferase

• SKU: MEXHY-170792-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170792-0
• Package Unit: Get quote
• Quantity Unit: STK