Product Description: PROTAC BET Degrader-1 is a PROTAC connected by ligands for Cereblon and BET, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration.
Applications: Cancer-programmed cell death
Formula: C44H45N11O9
References: [1]Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.
CAS Number: 2093386-22-0
Molecular Weight: 871.90
Compound Purity: 99.41
Research Area: Cancer
Solubility: DMSO : ≥ 50 mg/mL
Target: Epigenetic Reader Domain;PROTACs