Product Description: PROTAC c-Myc degrader-1 (Compound A153) is a multiple target protein degrader (PROTAC). PROTAC c-Myc degrader-1 effective degrades c-MYC, CK1α, GSPT1 and IKZF1/2/3 proteins in a variety of tumor cells. PROTAC c-Myc degrader-1 can be used for c-Myc high expression related disease research, such as cancer, cardiovascular and cerebrovascular diseases, and viral infection (Pink: c-Myc ligand (HY-168685); Blue: E3 ligase ligand (HY-W093472); Black: linker (HY-W015808))[1].
Applications: COVID-19-anti-virus
Formula: C35H30N6O5
References: [1]TONG YOUZHI, et al. 2,6-Dioxopiperidine compounds as c-Myc inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2022268066. 2022.
CAS Number: 2883535-99-5
Molecular Weight: 614.65
Research Area: Cancer; Infection; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Casein Kinase;c-Myc;PROTACs
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