PROTAC HDAC6 degrader 2

Product Description: PROTAC HDAC6 degrader 2 (Compound 1) is a HDAC6 PROTAC degrader, with IC50 of 0.643 μM. PROTAC HDAC6 degrader 2 promotes ubiquitination and degradation of HDAC6. PROTAC HDAC6 degrader 2 can be used for the research of haematological and solid cancers (Pink: HDAC6 ligand (HY-171141); Blue: E3 ligase CRBN ligand (HY-10984))[1].

Formula: C34H33F2N9O8

References: [1]Keuler T, et al. Development of the first non-hydroxamate selective HDAC6 degraders. Chem Commun (Camb). 2022 Oct 4;58(79):11087-11090.

Molecular Weight: 733.68

Compound Purity: 99.80

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: HDAC;PROTACs

• SKU: MEXHY-171139-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171139-5
• Package Unit: 5 mg
• Quantity Unit: STK