PROTAC HDAC6 degrader 3

Product Description: PROTAC HDAC6 degrader 3 (Compound 4) is a selective inhibitor and degrader for HDAC6 with an IC50 of 686 nM and a DC50 of 171 nM. PROTAC HDAC6 degrader 3 promotes the acetylation of α-tubulin[1]. (Pink: ligand for target protein (HY-171141); Blue: ligand for E3 ligase VHL (HY-150803))

Formula: C46H56F2N10O9S

References: [1]Keuler T, et al., Development of the first non-hydroxamate selective HDAC6 degraders. Chem Commun (Camb). 2022 Oct 4;58(79):11087-11090.

Molecular Weight: 963.06

Compound Purity: 99.81

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: HDAC;PROTACs

• SKU: MEXHY-171140-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171140-5
• Package Unit: 5 mg
• Quantity Unit: STK