PSSI-51

Product Description: PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders[1].

Formula: C28H29Cl2F2N3O2

References: [1]Tabatabaei Dakhili, et al. Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity. iScience, Volume 28, Issue 5, 1123361.

Molecular Weight: 548.45

Research Area: Metabolic Disease

Target: Others

• SKU: MEXHY-173527-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173527-0
• Package Unit: Get quote
• Quantity Unit: STK