(R)-Crinecerfont, CAS 2649012-21-3

Product Description: (R)-Crinecerfont is the R-enantiomer of Crinecerfont (HY-106203). Crinecerfont (SSR-125543) is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research. Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].

Formula: C27H28ClFN2OS

References: [1]Newfield RS, et al. Crinecerfont, a CRF1 Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia. J Clin Endocrinol Metab. 2023 Oct 18;108(11):2871-2878.

CAS Number: 2649012-21-3

Molecular Weight: 483.04

Research Area: Metabolic Disease

Target: CFTR

• SKU: MEXHY-106203B-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106203B-10
• Package Unit: 10 mg
• Quantity Unit: STK