(Rac)-AMG8379, CAS 1641574-26-6

Product Description: (Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide antagonist of NaV1.7, with IC50s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7, respectively [1].

Applications: Neuroscience-Neuromodulation

Formula: C25H16ClF2N3O5S

References: [1]Kornecook TJ, et al. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7. J Pharmacol Exp Ther. 2017 Jul;362(1):146-160.

CAS Number: 1641574-26-6

Molecular Weight: 543.93

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Sodium Channel

• SKU: MEXHY-108425B-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108425B-1
• Package Unit: 1 mg
• Quantity Unit: STK