RIPK2/3-IN-2

Product Description: RIPK2/3-IN-2 (29) is a dual RIPK2 and RIPK3 inhibitor, with IC50 values of 12 nM and 18 nM, respectively. RIPK2/3-IN-2 (29) induces necroptosis, with an EC50 of 0.16 μM[1].

Formula: C23H20FN5O

References: [1]Duo Ma, et al. Discovery of Potent and Balanced Dual RIPK2 and 3 Inhibitors as a New Strategy for the Treatment of Inflammatory Bowel Diseases. J Med Chem. 2025 Apr 10;68(7):7539-7559.

Molecular Weight: 401.44

Research Area: Inflammation/Immunology

Target: RIP kinase

• SKU: MEXHY-173454-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173454-0
• Package Unit: Get quote
• Quantity Unit: STK