RNA recruiter 1

Product Description: RNA recruiter 1 is the RNA ligand of RNAse L RIBOTAC (HY-168456), an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. RNA recruiter 1 can be utilized in the synthesis of RIBOTAC[1].

Formula: C20H18N4O3

References: [1]Tang Z, et al. Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5' untranslated region. Nat Commun. 2025 Jan 8;16(1):483.

Molecular Weight: 362.38

Research Area: Infection

Target: Ligands for Target Protein for PROTAC

• SKU: MEXHY-168456-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168456-0
• Package Unit: Get quote
• Quantity Unit: STK