RNAse L RIBOTAC

Product Description: RNAse L RIBOTAC (compound C64) is an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. (Blue: RNA ligand (HY-168456); Black: linker (HY-130591); Pink: Rnase L ligand (HY-168457))[1]

Formula: C55H60N8O13S

References: [1]Tang Z, et al. Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5' untranslated region. Nat Commun. 2025 Jan 8;16(1):483.

Molecular Weight: 1073.18

Research Area: Infection

Target: PROTACs

• SKU: MEXHY-168455-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168455-0
• Package Unit: Get quote
• Quantity Unit: STK