Roflumilast N-oxide (Standard), CAS 292135-78-5

Product Description: Roflumilast N-oxide (Standard) is the analytical standard of Roflumilast N-oxide. This product is intended for research and analytical applications. Roflumilast N-oxide is a PDE type 4 inhibitor.

Formula: C17H14Cl2F2N2O4

References: [1]Victoni T, et al. Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells. Int Immunopharmacol. 2016 Jan;30:1-8./[2]Milara J,et al. Simvastatin Increases the Ability of Roflumilast N-oxide to Inhibit Cigarette Smoke-Induced Epithelial to Mesenchymal Transition in Well-differentiated Human Bronchial Epithelial Cells in vitro. COPD. 2015 Jun;12(3):320-31./[3]Vollert S, et al. The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db mice. Diabetologia. 2012 Oct;55(10):2779-2788.

CAS Number: 292135-78-5

Molecular Weight: 419.21

Research Area: Inflammation/Immunology

Target: Drug Metabolite;Phosphodiesterase (PDE);Reference Standards

• SKU: MEXHY-100639R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100639R-0
• Package Unit: Get quote
• Quantity Unit: STK