ROS inducer 8

Product Description: ROS inducer 8 (Compound 11g) is the inhibitor for glutathione (GSH), that induces the ROS accumulation in Enterococcus faecalis, thereby exhibiting antibacterial activity. ROS inducer 8 disrupts the biofilm, inhibits S. aureus and E. faecalis with MIC of 8 μg/mL and 2 μg/mL, exhibits post-antibiotic effect. ROS inducer 8 exhibits low hemolytic toxicity to sheep erythrocytes (HC50 > 1280 μg/mL)[1].

Formula: C26H31FN6O6

References: [1]Ampomah-Wireko M, et al., Design, synthesis and antibacterial evaluation of oxazolidinone derivatives containing N-methylglycyl or quaternary ammonium salts. Bioorg Med Chem. 2025 Mar 2;122:118144.

Molecular Weight: 542.56

Research Area: Infection

Target: Bacterial;Reactive Oxygen Species

• SKU: MEXHY-168960-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168960-0
• Package Unit: Get quote
• Quantity Unit: STK