Product Description: RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].
Formula: C33H38N4O8
References: [1]Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan. Anal Chem. 2018 May 15;90(10):6012-6019.
CAS Number: 181467-56-1
Molecular Weight: 618.68
Research Area: Cancer
Target: Cholinesterase (ChE);Drug Metabolite;Reference Standards;Topoisomerase