(S)-GSK-F1, CAS 1384097-27-1

Product Description: (S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα). (S)-GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα, PI3Kβ and PI3Kδ with pIC50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model[1].

Applications: COVID-19-anti-virus

Formula: C27H18F5N5O4S

References: [1]Leivers AL, et al., Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents. J Med Chem. 2014 Mar 13;57(5):2091-106.

CAS Number: 1384097-27-1

Molecular Weight: 603.52

Research Area: Infection

Target: PI3K;PI4K

• SKU: MEXHY-100603A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100603A-1
• Package Unit: 1 mg
• Quantity Unit: STK