(S)-Roscovitine, CAS 186692-45-5

Product Description: (S)-Roscovitine ((S)-Seliciclib; (S)-CYC202) is a potent and cross the blood-brain barrier CDKs inhibitor. (S)-Roscovitine shows neuroprotective efficacy. (S)-Roscovitine has the potential for the research of stroke[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C19H26N6O

References: [1]Le Roy L, et al. Cellular and Molecular Mechanisms of R/S-Roscovitine and CDKs Related Inhibition under Both Focal and Global Cerebral Ischemia: A Focus on Neurovascular Unit and Immune Cells. Cells. 2021 Jan 8;10(1):104./[2]Menn B, et al. Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models. PLoS One. 2010 Aug 12;5(8):e12117.

CAS Number: 186692-45-5

Molecular Weight: 354.45

Compound Purity: 99.15

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: CDK

• SKU: MEXHY-112403-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112403-50
• Package Unit: 50 mg
• Quantity Unit: STK