Product Description: SARS-CoV-2-IN-110 (compound Bb1) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-110 exhibits antiviral efficacy against SARS-CoV-2 with an EC50 of 1.10 μM and significantly lower toxicity compared to Lapatinib (HY-50898). SARS-CoV-2-IN-110 inhibits SARS-CoV-2 with a CC50 of > 100 μM, with a selectivity index (SI) of >91[1].
Applications: COVID-19-anti-virus
Formula: C28H20ClFN4O2
References: [1]Adediji A, et al. Design, synthesis, and antiviral activity of fragmented-lapatinib aminoquinazoline analogs towards SARS-CoV-2 inhibition. Eur J Med Chem. 2025 Mar 15;286:117303.
Molecular Weight: 498.94
Research Area: Infection
Target: SARS-CoV