SARS-CoV-2 Mpro-IN-37

Product Description: SARS-CoV-2 Mpro-IN-37 (compound 8r) is a SARS-CoV-2 main protease (Mpro) inhibitor, with an IC50 of 0.0199 μM. SARS-CoV-2 Mpro-IN-37 inhibits SARS-CoV-1 Mpro and MERS-CoV Mpro with IC50s of 0.00945 and 0.111 μM, respectively. SARS-CoV-2 Mpro-IN-37 displays high antiviral activity in the nanomolar range without showing cellular toxicity[1].

Formula: C25H30N2O3S

References: [1]Flury P, et al. Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity. J Med Chem. 2025 Feb 13;68(3):3626-3652.

Molecular Weight: 438.58

Research Area: Infection

Target: SARS-CoV

• SKU: MEXHY-170894-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170894-0
• Package Unit: Get quote
• Quantity Unit: STK