SARS-CoV-2 Mpro-IN-9, CAS 2754370-99-3

Product Description: SARS-CoV-2 Mpro-IN-9 (compound c7) is a nonpeptidic, noncovalent SARS-CoV-2 Mpro inhibitor (IC50=0.085 μM), with improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. SARS-CoV-2 Mpro-IN-9 inhibits viral replication (EC50=1.10 μM) in SARS-CoV-2-infected Vero E6 cells, while exhibits low cytotoxic effects (CC50>50 μM)[1].

Applications: COVID-19-anti-virus

Formula: C20H14N2O4

References: [1]Zhang K, et al. Discovery of quinazolin-4-one-based non-covalent inhibitors targeting the severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2 Mpro). Eur J Med Chem. 2023 Sep 5;257:115487.

CAS Number: 2754370-99-3

Molecular Weight: 346.34

Research Area: Infection

Solubility: 10 mM in DMSO

Target: SARS-CoV

• SKU: MEXHY-155527-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155527-5
• Package Unit: 5 mg
• Quantity Unit: STK