Shelf life (days): 1460
Info: An NK1 and NK2 receptor peptide agonist; binds to membrane preparations of rat submandibular gland and hamster urinary bladder (Kis = 0.9 and 2 nM, respectively), tissues that endogenously express high levels of NK1 and NK2 receptors, respectively; increases intracellular levels of IP3 in KNRK rat kidney cells expressing the NK1 receptor at 1 µM; induces contractions in isolated and perfused carp intestinal bulb smooth muscle strips (EC50 = 15 nM); induces reciprocal hindlimb neck-scratching behavior in mice (ED50s = 0.07 and 0.05 nmol/animal, i.t. and i.c.v., respectively)
Formulation: A solid
Formal Name: L-alanyl-L-lysyl-L-phenylalanyl-L-α-aspartyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-L-methioninamide, trifluoroacetate salt
Amino Acids: AKFDKFYGLM-NH2
Purity: ≥95%
Formula Markup: C59H87N13O13S • XCF3COOH
Formula Weight: 1218.483
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