SDM-8, CAS 2242777-37-1

Product Description: SDM-8 is a difluoro-analog of UCB-J (HY-136873).SDM-8 shows high SV2A binding affinity with a Ki of 0.58 nM. SDM-8 can be used in the study of Alzheimer's disease[1].

Applications: Neuroscience-Neurodegeneration

Formula: C17H16F2N2O

References: [1]Li S, et al. Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates. ACS Chem Neurosci. 2019 Mar 20;10(3):1544-1554.

CAS Number: 2242777-37-1

Molecular Weight: 302.32

Research Area: Neurological Disease

Target: Radionuclide-Drug Conjugates (RDCs)

• SKU: MEXHY-167830-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-167830-5
• Package Unit: 5 mg
• Quantity Unit: STK