SIC-19, CAS 713112-69-7

Product Description: SIC-19 is a SIK2 inhibitor and promotes SIK2 protein degradation via the ubiquitination pathway. SIC-19 inhibits cancer cell growth and sensitizes cells to PARP inhibitors (Such as Olaparib (HY-10162)), as well as in ovarian cancer organoids and xenograft models[1].

Formula: C29H26N4O5S2

References: [1]Wang F, et al. A novel SIK2 inhibitor SIC-19 exhibits synthetic lethality with PARP inhibitors in ovarian cancer. Drug Resist Updat. 2024 May;74:101077.

CAS Number: 713112-69-7

Molecular Weight: 574.67

Research Area: Cancer

Target: Salt-inducible Kinase (SIK)

• SKU: MEXHY-163743-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163743-50
• Package Unit: 50 mg
• Quantity Unit: STK