SIK2/3-IN-1, CAS 3038863-24-7

Product Description: SIK2/3-IN-1 (Compound 7S) is a selectively inhibitory agent of SIK2/3 with oral activity. SIK2/3-IN-1 can significantly inhibit tumor growth (without any body weight loss) in the MV4-11 AML mice CDX model. SIK2/3-IN-1 can be used in the research of MEF2C-dependent acute myeloid leukemia[1].

Formula: C20H19F3N6O2

References: [1]Zhu W, et al. Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+ Acute Myeloid Leukemia (AML). J Med Chem. 2025 Apr 10;68(7):7518-7538.

CAS Number: 3038863-24-7

Molecular Weight: 432.40

Research Area: Cancer

Target: Salt-inducible Kinase (SIK)

• SKU: MEXHY-170237-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170237-0
• Package Unit: Get quote
• Quantity Unit: STK