SIRT2/6-IN-1, CAS 1214468-35-5

Product Description: SIRT2/6-IN-1 (Compound 5) is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. SIRT2/6-IN-1 increases H3K9 acetylation, increases glucose uptake and reduces TNF-α secretion in cells[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C19H14N4O5S

References: [1]Parenti MD, et al. Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12;57(11):4796-804.

CAS Number: 1214468-35-5

Molecular Weight: 410.40

Compound Purity: 99.79

Research Area: Metabolic Disease

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Histone Demethylase;Sirtuin

• SKU: MEXHY-123194-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-123194-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK