ssRNA42 (sodium)

Product Description: ssRNA42 (sodium) is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. ssRNA42 (sodium) derives from ssRNA40 by replacement of all G nucleotides with adenosine. ssRNA42 activated human PBMCs to secrete IFN-α, TNF-a, IL- 12p40, and IL-6, but ssRNA42 failed to stimulated murine pDCs and PBMCs.

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Hiromi Tanji, et al. Toll-like receptor 8 senses degradation products of single-stranded RNA. Nat Struct Mol Biol. 2015, 22, 2.

Molecular Weight: N/A

Compound Purity: 98.62

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO/10 mM in H2O

Target: Toll-like Receptor (TLR)

• SKU: MEXHY-160231-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160231-1
• Package Unit: 1 mg
• Quantity Unit: STK