STAT5-IN-3

Product Description: STAT5-IN-3 (Compound 14a) is a STAT5 inhibitor with anticancer activity. STAT5-IN-3 blocks the tyrosine phosphorylation of STAT5A/5B at the Y694/699 sites and significantly reduces the expression of STAT5B protein, thereby inhibiting downstream gene transcription and blocking the proliferation and survival of leukemia cells. Additionally, STAT5-IN-3 holds significant value in overcoming chemotherapy resistance[1].

Formula: C25H27N5O

References: [1]Polomski M, et al. Novel antileukemic compound with sub-micromolar potency against STAT5 addicted myeloid leukemia cells. Eur J Med Chem. 2025 Feb 15;284:117211.

Molecular Weight: 413.51

Research Area: Cancer

Target: STAT

• SKU: MEXHY-170837-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170837-0
• Package Unit: Get quote
• Quantity Unit: STK