STING-IN-11, CAS 2925028-15-3

Product Description: STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING-mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING-related inflammatory and autoimmune diseases[1].

Formula: C21H20ClF2N3O

References: [1]Han X, et al. Discovery of an Orally Bioavailable STING Inhibitor with In Vivo Anti-Inflammatory Activity in Mice with STING-Mediated Inflammation. J Med Chem. 2025 Feb 13;68(3):2963-2980.

CAS Number: 2925028-15-3

Molecular Weight: 403.85

Research Area: Inflammation/Immunology

Target: Interleukin Related;STING

• SKU: MEXHY-170949-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170949-0
• Package Unit: Get quote
• Quantity Unit: STK