STING-IN-12

Product Description: STING-IN-12 (compound Y2) is an inhibitor of STING. STING-IN-12 inhibits IFNβ gene expression (IC50=0.75μM) induced by SR717. STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and MSA-2-induced STING pathway activation in vivo in mice[1].

Formula: C15H13F3N2O5

References: [1]Liang Xue, et al. Design, synthesis, and activity evaluation of novel STING inhibitors based on C170 and H151. Eur J Med Chem. 2025 Jun 5:290:117533.

Molecular Weight: 358.27

Research Area: Inflammation/Immunology

Target: STING

• SKU: MEXHY-173316-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173316-0
• Package Unit: Get quote
• Quantity Unit: STK