T-0156 (free base), CAS 324572-92-1

Product Description: T-0156 free base is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor. T-0156 free base specifically inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) by PDE5 in a competitive manner (IC50=0.23 nM). T-0156 free base inhibits PDE6 (IC50=56 nM) and has low potencies against PDE1, PDE2, PDE3, and PDE4 (IC50>10 μM). T-0156 free base enhances the nitric oxide (NO)/cGMP pathway[1].

Formula: C31H29N5O7

References: [1]Hideki Mochida, et al. Enzymological and pharmacological profile of T-0156, a potent and selective phosphodiesterase type 5 inhibitor. Eur J Pharmacol. 2002 Dec 5;456(1-3):91-8.

CAS Number: 324572-92-1

Molecular Weight: 583.59

Research Area: Neurological Disease

Target: Phosphodiesterase (PDE)

• SKU: MEXHY-164685-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164685-1
• Package Unit: 1 mg
• Quantity Unit: STK