TDK-HCPT

Product Description: TDK-HCPT is a small-molecule conjugate that links glutathione-sensitive thiamine disulfide to the chemotherapy drug 10-Hydroxycamptothecin (HY-N0095) via a thioketal bond. TDK-HCPT can target tumor cells and prolong the retention of chemotherapy agents within tumor cells. TDK-HCPT can inhibit tumor growth, induce apoptosis of tumor cells, and has anti-tumor activity[1].

Formula: C42H53N3O9S4

References: [1]Yang C, et al. An oxidation-reduction-triggered thiamine disulfide-based prodrug of 10-hydroxycamptothecin for selective tumor cell locking and therapeutic delivery. Eur J Med Chem. 2025 Feb 15;284:117233.

Molecular Weight: 872.14

Research Area: Cancer

Target: Apoptosis

• SKU: MEXHY-170842-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170842-0
• Package Unit: Get quote
• Quantity Unit: STK