Product Description: tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents[1][2].
Formula: C6H10Cl3NO
References: [1]Fandrick KR, et al. A Noncoordinating Acid-Base Catalyst for the Mild and Nonreversible tert-Butylation of Alcohols and Phenols. J Org Chem. 2021 Mar 19;86(6):4877-4882./[2]Evans LE, et al. Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a β-Lactamase-Activated Antibacterial Prodrug. J Med Chem. 2019 May 9;62(9):4411-4425.
CAS Number: 98946-18-0
Molecular Weight: 218.51
Compound Purity: 99.48
Research Area: Infection
Target: Bacterial;Drug Intermediate