Thalidomide 4'-ether-PEG1-azide, CAS 2758432-02-7

Product Description: Thalidomide 4'-ether-PEG1-azide is the Thalidomide (HY-14658)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4'-ether-PEG1-azide can be connected to the ligand for protein by a linker to form PROTACs[1].

Applications: Cancer-programmed cell death

Formula: C17H17N5O6

References: [1]Chen P, et al. α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship. Bioorg Chem. 2021 Nov;116:105295.

CAS Number: 2758432-02-7

Molecular Weight: 387.35

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-157514-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157514-25
• Package Unit: 25 mg
• Quantity Unit: STK