Thalidomide-NH-C9-NH2 (hydrochloride), CAS 2305936-77-8

Product Description: Thalidomide-NH-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].

Applications: Cancer-programmed cell death

Formula: C22H31ClN4O4

References: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.  [Content Brief]

CAS Number: 2305936-77-8

Molecular Weight: 450.96

Compound Purity: 99.85

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-156159-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156159-25
• Package Unit: 25 mg
• Quantity Unit: STK