TNF-α agonistic 1, CAS 2379727-88-3

Product Description: TNF-α agonistic 1 (compound 22a) can repolarize tumor-associated macrophages (TAMs) in the tumor microenvironment (TME) from the M2 phenotype to the M1 anti-tumor phenotype[1].

Applications: Cancer-programmed cell death

Formula: C24H21ClF3N5O

References: [1]Pei H, et al. Discovery of potent ureido tetrahydrocarbazole derivatives for cancer treatments through targeting tumor-associated macrophages. Eur J Med Chem. 2019 Dec 1;183:111741.

CAS Number: 2379727-88-3

Molecular Weight: 487.90

Research Area: cancer

Target: TNF Receptor

• SKU: MEXHY-163642-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163642-5
• Package Unit: 5 mg
• Quantity Unit: STK