TNKS-IN-3

Product Description: TNKS-IN-3 (Compound 6) is a TNKS2 inhibitor (Ki: 8.5 nM). TNKS-IN-3 has good activity (IC50: 71 nM) and can effectively inhibit the WNT/β-catenin signaling pathway. TNKS-IN-3 can be used in the research of diseases such as cancer and fibrosis[1].

Formula: C30H27N5O4S

References: [1]Sowa ST, et al. Deconstruction of Dual-Site Tankyrase Inhibitors Provides Insights into Binding Energetics and Suggests Critical Hotspots for Ligand Optimization. J Med Chem. 2025 Apr 10;68(7):7263-7279.

Molecular Weight: 553.63

Research Area: Cancer

Target: PARP

• SKU: MEXHY-173480-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173480-0
• Package Unit: Get quote
• Quantity Unit: STK