Tolvaptan (Standard), CAS 150683-30-0

Product Description: Tolvaptan (Standard) is the analytical standard of Tolvaptan. This product is intended for research and analytical applications. Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia[1][2].

Formula: C26H25ClN2O3

References: [1]Wu Y, et al. Mechanisms of tolvaptan-induced toxicity in HepG2 cells. Biochem Pharmacol. 2015 Jun 15;95(4):324-36./[2]El-Shabrawy M, et al. Protective effect of tolvaptan against cyclophosphamide-induced nephrotoxicity in rat models. Pharmacol Res Perspect. 2020 Oct;8(5):e00659.

CAS Number: 150683-30-0

Molecular Weight: 448.94

Research Area: Cardiovascular Disease; Endocrinology; Cancer

Target: Autophagy;Reference Standards;Vasopressin Receptor

• SKU: MEXHY-17000R-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17000R-25
• Package Unit: 25 mg
• Quantity Unit: STK