TRAP1-IN-1, CAS 3031102-94-7

Product Description: TRAP1-IN-1 (compound 35) is a potent and selective inhibitor of TRAP1，a mitochondrial isoform of Hsp90. TRAP1-IN-1 has >250-fold TRAP1 selectivity over Grp94，and disrupts TRAP1 tetramer stability，induces TRAP1 client protein degradation. TRAP1-IN-1 also inhibits mitochondrial complex I of oxidative phosphorylation OXPHOS，disrupts the mitochondrial membrane potential，and enhances glycolysis metabolism[1].

Applications: Cancer-Kinase/protease

Formula: C45H39F7N2O4P2

References: [1]Merfeld T, et al. Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes. Eur J Med Chem. 2023 Oct 5;258:115531.

CAS Number: 3031102-94-7

Molecular Weight: 866.74

Compound Purity: 96.03

Research Area: Cancer

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: HSP;Mitochondrial Metabolism

• SKU: MEXHY-155063-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155063-10
• Package Unit: 10 mg
• Quantity Unit: STK