TRF2-IN-1

Product Description: TRF2-IN-1 (compound F2) is a potent telomere repeat-binding factor 2 (TRF2) inhibitor. TRF2-IN-1 shows antiproliferative activity. TRF2-IN-1 induces apoptosis. TRF2-IN-1 directly bind to the TRF2TRFH domain and selectively inhibits TRF2 protein expression and telomeric localization. TRF2-IN-1 shows anticancer activity. TRF2-IN-1 has the potential for the research of osteosarcoma[1].

Formula: C18H17BrO4

References: [1]Wang K, et al. Design, synthesis, and biological evaluation of Flavokavain B derivatives as potent TRF2 inhibitors for the treatment of Osteosarcoma. Eur J Med Chem. 2025 Mar 15;286:117279.

Molecular Weight: 377.23

Research Area: Cancer

Target: Apoptosis;Telomerase

• SKU: MEXHY-168890-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168890-0
• Package Unit: Get quote
• Quantity Unit: STK