TRPM7-IN-1, CAS 1909225-07-5

TRPM7-IN-1, CAS 1909225-07-5
SKU
MEXHY-168608-25
Packaging Unit
25 mg
Manufacturer
MedChemExpress

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Product Description: TRPM7-IN-1 (compound SUD), a benzoylurea derivative, is an effective TRPM7 inhibitor. TRPM7-IN-1 induces cell cycle arrest and apoptosis, decreases the migration of MCF-7 and BGC-823 cells. TRPM7-IN-1 decreases vimentin expression and increases E-cadherin expression. TRPM7-IN-1 potentially reduces the TRPM7-like current and decreases TRPM7 expression through the PI3K/Akt signaling pathway. TRPM7-IN-1 is a potential agent to suppress the metastasis of breast and gastric cancer by inhibiting TRPM7 expression and function[1].

Formula: C23H25N5O3

References: [1]Xiaoding Zhang, et al. Novel benzoylurea derivative decreases TRPM7 channel function and inhibits cancer cells migration. Channels (Austin). 2024 Dec;18(1):2396339.

CAS Number: 1909225-07-5

Molecular Weight: 419.48

Research Area: Cancer

Target: Akt;Apoptosis;PI3K;TRP Channel
More Information
SKU MEXHY-168608-25
Manufacturer MedChemExpress
Manufacturer SKU HY-168608-25
Package Unit 25 mg
Quantity Unit STK
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