UP163, CAS 591242-60-3

Product Description: UP163 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 9.0 μM. UP163 reduces MG-132 (HY-13259)-induced TDP-43 aggregates[1].

Formula: C20H15ClN2O5S

References: [1]Phan JM, et al., VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models. J Clin Invest. 2024 May 23;134(14):e169039.

CAS Number: 591242-60-3

Molecular Weight: 430.86

Compound Purity: 98.08

Research Area: Others

Target: p97

• SKU: MEXHY-168323-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-168323-10
• Package Unit: 10 mg
• Quantity Unit: STK