Urease-IN-20, CAS 2998940-98-8

Product Description: Urease-IN-20 (compound XBP2) is an inhibitor of Helicobacter pylori (H. pylori). Urease-IN-20 inhibits H. pylori with an IC50 of 0.14 μM. Urease-IN-20 reduces cell Apoptosis and decreases ROS and γH2AX in GES-1 cells infected with H. pylori. Urease-IN-20 exhibits significant gastric mucosal protective effects. Urease-IN-20 shows the potential for H. pylori research[1].

Applications: COVID-19-immunoregulation

Formula: C14H8FNO2Se

References: [1]Cao W, et al. Synthesis and evaluation of novel ebselen derivatives as urease inhibitors for combating Helicobacter pylori infections. Eur J Med Chem. 2025 Apr 5;287:117359.

CAS Number: 2998940-98-8

Molecular Weight: 320.18

Research Area: Infection

Target: Apoptosis;Bacterial;Reactive Oxygen Species

• SKU: MEXHY-170937-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-170937-0
• Package Unit: Get quote
• Quantity Unit: STK