Val-Ala-PABC-Exatecan, CAS 2845164-91-0

Product Description: Val-Ala-PABC-Exatecan is a Drug-Linker Conjugates for ADC，consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor，HY-13631). Val-Ala-PABC-Exatecan can be used for ADC molecues synthesis，such as Mal-PEGn-amide-va-Exatecan[1].

Applications: Cancer-programmed cell death

Formula: C40H43FN6O8

References: [1]Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.

CAS Number: 2845164-91-0

Molecular Weight: 754.80

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : 200 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• SKU: MEXHY-147095-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147095-1
• Package Unit: 1 mg
• Quantity Unit: STK