Product Description: VK-II-86 is a Carvedilol (HY-B0006) analogue lacking antagonist activity at β-adrenoceptors, in hypokalaemia. VK-II-86 prevents hypokalaemia-induced ventricular arrhythmia through multi-channel effects. VK-II-86 prevents all hypokalaemia-induced changes in ion channel activity and oxidative stress[1].
Applications: Neuroscience-Neuromodulation
Formula: C25H28N2O4
References: [1]Robinson VM, et al. A carvedilol analogue, VK-II-86, prevents hypokalaemia-induced ventricular arrhythmia through novel multi-channel effects. Br J Pharmacol. 2022 Jun;179(11):2713-2732.
CAS Number: 955371-84-3
Molecular Weight: 420.50
Compound Purity: 93.3
Research Area: Cardiovascular Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Others