VX-702 (Standard), CAS 745833-23-2

Product Description: VX-702 (Standard) is the analytical standard of VX-702. This product is intended for research and analytical applications. VX-702 is a highly selective inhibitor of p38α MAPK, 14-fold higher potency against the p38α versus p38β[1].

Formula: C19H12F4N4O2

References: [1]Kuliopulos A, et al. Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation. Thromb Haemost, 2004, 92(6), 1387-1393./[2]Braddock M, IDDB Meeting Report, 2005, March 14-15./[3]Gill A, IDDB Meeing Report, 2002, March 06-08./[4]Naka K, et al. Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells. Nat Commun. 2015 Aug 20;6:8039.

CAS Number: 745833-23-2

Molecular Weight: 404.32

Research Area: Inflammation/Immunology

Target: Autophagy;p38 MAPK;Reference Standards

• SKU: MEXHY-10401R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10401R-0
• Package Unit: Get quote
• Quantity Unit: STK