YX968, CAS 2742732-92-7

Product Description: YX968 is a potent and selective HDAC3/8 PROTAC dual degrader with DC50 values of 1.7 and 6.8 nM. YX968 exhibits antitumor activity by promoting apoptosis[1].(Pink: Target protein ligand (HY-168287); Black: linker (HY-W007700); Blue: E3 ligase ligand (HY-112078))

Applications: Cancer-programmed cell death

Formula: C45H66N8O5S

References: [1]Xiao Y, et al. HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation. Cell Chem Biol. 2023 Nov 16;30(11):1421-1435.e12.

CAS Number: 2742732-92-7

Molecular Weight: 831.12

Compound Purity: 98.06

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;HDAC;PROTACs

• SKU: MEXHY-164233-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164233-1
• Package Unit: 1 mg
• Quantity Unit: STK